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Timothy J. Ley is an American hematologist and cancer biologist. He is the Lewis T. and Rosalind B. Apple Professor of Oncology in the Department of Medicine, is chief of the Section of Stem Cell Biology in the Division of Oncology and is Professor of Genetics at Washington University in St. Louis. He is an associate director of the McDonnell Genome Institute at Washington University and is affiliated with the Alvin J. Siteman Cancer Center.〔(【引用サイトリンク】 url = http://www.siteman.wustl.edu/ResearcherProfile.aspx?id=1006&memid=88 )〕 Dr. Ley's research group focuses on the genetics and genomics of acute myeloid leukemia (AML). His lab studies the development of normal and leukemic blood cells. His work is focused on identifying the mutations that are responsible for the initiation and progression of AML.〔("Cancer gene complexity revealed." ) "BBC News". 7 August 2009.〕 Dr. Ley led the team that sequenced the first cancer genome (of an AML patient).〔("Experts Decode Cancer Patient's Genes, Seeking Treatment Clues." ) ''New York Times''. 6 November 2008.〕 He has gone on to develop projects that will use whole genome sequencing to help diagnose and treat patients with leukemia.〔("In Treatment for Leukemia, Glimpses of the Future." ) "New York Times". 7 July 2012.〕 To better understand the role of many of the mutations discovered through whole genome sequencing of leukemias, he and his colleagues have constructed several mouse models of acute promyelocytic leukemia (APL), which are very similar to human APL.〔(Siteman Cancer Center History )〕 Dr. Ley's laboratory has also extensively defined the roles of granzymes for the functions of cytotoxic and regulatory T cells.〔(Siteman Cancer Center Profile )〕 Dr. Ley grew up in Lakota, Iowa. He received his B.A. degree from Drake University in 1974, and his M.D. from Washington University School of Medicine in 1978. He did his internship and residency in Medicine at Massachusetts General Hospital, was a Clinical Associate at the NHLBI (National Heart, Lung, and Blood Institute), a Hematology-Oncology Fellow at Washington University Medical Center, and a Senior Investigator at the NHLBI before moving to Washington University in 1986. In 2015, Ley was appointed to the National Cancer Advisory Board by President Obama.〔(President Obama Announces More Key Administration Posts )〕 ==Awards and honors== *(Recipient, The Erasmus Hematology Award, ) Erasmus MC, 2015 *(Recipient, E. Donnall Thomas Prize, ) American Society of Hematology, 2012 *(Recipient, The George Engelmann Interdisciplinary Award, ) Academy of Science, St. Louis, 2012 *(Fellow, ) American Academy of Arts and Sciences, 2010 *(Best Doctors In America ), 2008 *(Treasurer, ) Association of American Physicians, 2007–Present *(Member ), Institute of Medicine, 2003 *(Fellow, ) American Association for the Advancement of Science, 2002 *(President, ) American Society for Clinical Investigation, 1997–1998 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Timothy J. Ley」の詳細全文を読む スポンサード リンク
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